外伤性颅内血肿急性期血浆D―二聚体检测的价值

[摘要] 目的 探讨外伤性颅内血肿急性期检测D-二聚体的临床价值。方法 方便选取2013年6月―2016年6月该院收治的90例外伤性颅内血肿患者为实验组，另择取同期90名健康志愿者为对照组，两组分别于入院初和健康体检时采血，常规检测血浆D-二聚体水平。对比观察对照组与实验组不同程度脑损伤患者D-二聚体水平间的差异性，观察实验组不同预后结果患者的D-二聚体水平变化。结果 实验组血浆D二聚体（297.1±38.5）μg/L，对照组血浆D二聚体（113.7±21.4）μg/L，比较差异有统计学意义（P

[关键词] 颅脑外伤；颅内血肿；急性期；D-二聚体；检测价值

[中图分类号] R466 [文献标识码] A [文章编号] 1674-0742（2017）05（c）-0043-03

[Abstract] Objective To discuss the value of test of plasma D-dimer of traumatic intracranial hematoma during the acute period. Methods 90 cases of patients with traumatic intracranial hematoma in our hospital from June 2013 to June 2016 were convenient selected as the experimental group， and 90 cases of healthy volunteers at the same period were selected as the control group， and the blood of both groups was collected at the beginning of admission and at healthy physical examination， and the difference in the D-dimer of traumatic intracranial hematoma was compared between patients of different cerebral injuries， and the different prognosis results in the experimental group was observed and the changes of plasma D-dimer of patients were observed. Results The difference in the plasma D-dimer between the experimental group and the control group was statistically significant[（297.1±38.5）μg/L vs（113.7±21.4）μg/L]（P

[Key words] Cerebral injury； Intracranial hematoma； Acute period； D-dimer； Test value

B内血肿是颅脑损伤常见继发性病变，由创伤引起颅内血管破裂、血液积聚所致，近年来随着交通事故和工业意外的增多，发病率呈上升趋势[1]。现代研究发现，外伤性颅内血肿急性期凝血状态对预后存在影响，已引起临床广泛关注。D-二聚体是人体高凝状态和继发性纤溶亢进的重要分子标志物[2]。该研究以2013年6月―2016年6月该院收治的90例外伤性颅内血肿患者为例，对急性期血浆D-二聚体检测价值进行分析和探讨，现报道如下。

1 资料与方法

1.1 一般资料