硫酸镁早期干预急性胆源性胰腺炎疗效分析

时间:2022-10-09 01:25:39

硫酸镁早期干预急性胆源性胰腺炎疗效分析

摘要:目的:分析使用硫酸镁对急性胆源性胰腺炎进行早期干预的临床疗效。方法:随机从我院消化内科2011年6月-2013年6月收治的急性胆源性胰腺炎患者中选取70例作为研究对象,随机分成对照组和观察组,每组各35例。其中观察组使用硫酸镁进行早期干预,对照组则未进行干预,对比两组的治疗效果。结果:经对比,观察组患者的血淀粉酶降低率、体温以及白细胞降低、疼痛缓解和排便指标的改善率均显著高于对照组,且差异具有统计学意义(P<0.05)。同时,观察组患者的疼痛缓解率为85.71%;显著高于对照组的58.33%;急诊手术率为14.29%,显著低于对照组的33.33%,差异均具有统计学意义(P<0.05)。结论:使用硫酸镁对急性胆源性胰腺炎患者进行早期干预有助于改善患者的临床症状,减轻疾病痛苦,降低的急诊的手术率,具有显著疗效,值得临床推广应用。

关键词:硫酸镁;早期干预;急性胆源性胰腺炎;临床疗效

Abstract: Objective: Analysis of the use of magnesium sulfate on acute gallstone pancreatitis the clinical curative effect of early intervention.Methods: Random from our digestive internal medicine in June 2011 - June 2013 in patients with acute gallstone pancreatitis treated were selected 70 cases as the research object, randomly divided into control group and observation group, each group of 35 cases. Using magnesium sulfate for early intervention of group, control group did not intervene, compared two groups of treatment effect.Results: by contrast, the observation group of patients with blood amylase reduced rate, body temperature and white blood cells decreased, pain relief and defecation index of the period were significantly higher than that of control group, and the difference is statistically significant (P < 0.05). At the same time, the observation group of patients with pain relief rate was 85.71%; Is significantly higher than the control group 58.33%; Emergency operation rate was 14.29%, significantly less than 33.33% of the control group, the differences were statistically significant (P < 0.05). Conclusion: the use of magnesium sulfate for early intervention in patients with acute gallstone pancreatitis can help improve the patient's clinical symptoms, reduce the disease of pain, decrease the rate of emergency operation, has significant curative effect, worth clinical application.

Keywords: magnesium sulfate; Early intervention; Acute gallstone pancreatitis; Clinical curative effect

在消化内科的临床诊疗中,急性胆源性胰腺炎是一种比较常见的疾病,属于急腹症的范畴。该病具有发病快、病情变化快和病死率较高的特点,所以对其进行早期干预是非常有必要的[1]。为了探讨使用硫酸镁对急性胆源性胰腺炎进行早期干预的临床疗效,我院从2011年6月-2013年6月的相关患者中选取了70例进行研究,取得了显著效果,现报告如下。

1资料和方法

1.1 一般资料

随机从我院消化内科2011年6月-2013年6月收治的急性胆源性胰腺炎患者中选取70例作为研究对象,所有患者均符合急性胆源性胰腺炎的诊断标准,并分成对照组和观察组。对照组共35例,其中男11例,女24例,年龄为19-72岁,平均年龄为(57.8±6.3)岁。从疾病程度来看,21例为轻度患者,14例为重症患者。观察组共35例,其中男14例,女21例,年龄为20-78岁,平均年龄为(59.2±6.7)岁。从疾病程度来看,23例为轻度患者,12例为重症患者。从临床症状上看,两组患者均有不同程度的腹痛和尿淀粉酶升高表现,均于发病的6-8小时入院。对比两组的性别、年龄、疾病程度、临床表现和入院时间,差异不具有统计学意义(P>0.05),具有可比性。

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