镇咳汤治疗小儿支原体肺炎35例疗效观察

[摘要] 目的 观察自拟镇咳汤配合阿奇霉素治疗小儿支原体肺炎的临床疗效。 方法 将70例确诊支原体肺炎患儿随机分为观察组和对照组各35例。对照组予阿奇霉素治疗，观察组在对照组基础上予中药镇咳汤治疗，2个疗程后观察患儿疗效及临床症状、体征消失时间，随访6个月并复查血清肺炎支原体IgM抗体。 结果 观察组总有效率为100.0%，治愈率为65.7%，热退时间为（3.04±1.25） d，咳嗽消失时间为（7.68±2.35） d，肺部啰音消失时间为（8.16±2.47） d，复发率为8.5%；对照组总有效率为85.7%，治愈率为45.7%，热退时间为（4.60±2.05） d，咳嗽消失时间为（11.73±4.62） d，肺部啰音消失时间为（12.34±4.72） d，复发率为25.7%；两组比较差异有统计学意义（P < 0.05），观察组明显优于对照组。 结论 镇咳汤配合阿奇霉素治疗小儿支原体肺炎可较快改善病情，缩短病程，减少复发率。

[关键词] 小儿支原体肺炎；镇咳汤；阿奇霉素；中医治疗

[中图分类号] R272 [文献标识码] A [文章编号] 1674—4721（2012）09（c）—0108—02

Clinical effect observation of antitussive soup in treatment of 35 children with mycoplasma pneumonia

LIU Xiping

National Traditional Chinese Medicine Hospital of Xiangxi State in Hunan Province， Xiangxi 613000， China

[Abstract] Objective To observe clinical effect of antitussive soup in treatment of mycoplasma pneumonia in children. Methods Seventy cases of children with mycoplasma pneumonia were randomly divided into two groups. The control group was treated with azithromycin treatment， and the observation group was treated with antitussive decoction on the basis of the control group. Then the effect， the disappeared time of the clinical symptoms and signs were observed after 2 course of treatment. And the serum mycoplasma pneumoniae IgM antibodies were follow—up visited in 6 mouths. Results In the observation group， effective rate was 100.0%， cure rate was 94.3%， heat back time was （3.04±1.25） d， cough disappeared time was （7.68±2.35） d， lung sound disappear time was （8.16±2.47） d， recurrence rate was 8.5%. In the control group， effective rate was 85.7%， cure rate was 45.7%， heat back time was （4.60±2.05） d， cough disappeared time was （11.73±4.62） d， lung sound disappear time was （12.34±4.72） d， recurrence rate was 25.7%. Above indexes in the observation group were better than those in control group （P < 0.05）. Conclusion The antitussive soup with azithromycin in treatment of mycoplasma pneumonia can quickly improve disease， shorten the duration of symptoms and reduce the recurrence rate.

[Key words] Mycoplasma pneumonia； Antitussive soup； Azithromycin； Chinese medicine treatment

支原体肺炎（mycoplasmal pneumonia，MP）是小儿常见的一种非典型肺炎，以顽固性、刺激性咳嗽，发热或伴喘息为突出表现。临床中，西医采用大环内酯类抗生素治疗，但疗程长，症状改善慢，部分患儿病情迁延不愈或反复发作，给患儿及家属带来很大的痛苦，也引起临床医师的日益重视。笔者自2009年10月以来采用自拟镇咳汤配合阿奇霉素治疗小儿支原体肺炎35例，疗效满意，现报道如下：

1 资料与方法

1.1 一般资料

70例均为本院2009年10月～2011年12月儿科住院及门诊患儿，随机分为观察组和对照组各35例。观察组35例，其中，门诊患者8例，住院患者27例；病程3～15 d；男19例，女16例；年龄1～3岁18例，4～6岁10例，大于6岁7例。对照组35例，其中，门诊患者7例，住院患者28例；病程3～13 d；男17例，女18例；年龄1～3岁16例，4～6岁11例，大于6岁8例。两组均有咳嗽、发热等症状，两组患儿年龄、性别、病程、症状病情等比较，差异无统计学意义（P > 0.05），具有可比性。