妊娠期糖尿病不同治疗时机对母婴预后的临床研究

时间:2022-05-02 05:27:36

妊娠期糖尿病不同治疗时机对母婴预后的临床研究

[摘要] 目的 探讨妊娠期糖尿病不同治疗时机对母婴预后的临床观察。 方法 回顾性分析本院2010年1月~2012年1月住院分娩的76例妊娠期糖尿病患者,其中48例在孕中期确诊为妊娠期糖尿病并给予治疗,28例未行孕期保健或孕中期血糖筛查,于孕34周后住院确诊妊娠期糖尿病,将两组的妊娠结局进行比较。 结果 妊娠期糖尿病孕34周前治疗组中妊娠期高血压疾病、羊水过多、伤口感染、早产儿、新生儿窒息、巨大儿分别为14.6%、6.3%、4.2%、16.7%、4.2%、10.4%,均低于34周后治疗组,分别为21.4%、17.9%、14.3%、21.4%、7.1%、10.7%。 结论 妊娠期糖尿病对母婴危害大,及早诊断和治疗,可减少母婴并发症。

[关键词] 妊娠期;糖尿病;治疗时机;预后

[中图分类号] R714.256 [文献标识码] A [文章编号] 1674—4721(2012)09(c)—0045—02

Clinical research of influence of different treatment timing in gestational diabetes on prognosis of maternal and infant

ZHANG Xiaoyan HE Zhiying WANG Caihong

Department of Obstetrical, Houjie Hospital of Dongguan City in Guangdong Province, Dongguan 523960, China

[Abstract] Objective To explore the influence of different treatment timing in gestational diabetes on prognosis of maternal and infant. Methods Six cases of delivery patients with gestational diabetes in our hospital from January 2010 to January 2012 were analyzed retrospectively, among whom 48 cases were diagnosed with with gestational diabetes in the second trimester of pregnancy and given treatment, 28 cases did not carry out prenatal care or blood glucose screening in the second trimester of pregnancy, who were diagnosed with gestational diabetes after 34 weeks of pregnancy. The pregnancy outcomes between the two groups were compared. Results The incidence of hypertensive disorder complicating pregnancy, hydramnion, wound infection, premature infant, asphyxia neonatorum, macrosomia were 14.6%, 6.3%, 4.2%, 16.7%, 4.2%, 10.4% respectively in the gestational diabetes treatment group before 34 weeks of pregnancy, which were lower than 21.4%, 17.9%, 14.3%, 21.4%, 7.1%, 10.7% in the gestational diabetes treatment group after 34 weeks of pregnancy. Conclusion Gestational diabetes is harm for maternal and infants. Early diagnosis and treatment can reduce complications of maternal and infants.

[Key words] Pregnancy; Diabetes; Treatment timing; Prognosis

妊娠期糖尿病(gestational diabetes mellitus,GDM)是指妊娠期出现的糖耐量异常或糖尿病。一般妊娠结束糖尿病即可恢复。其发生率因种族不同和诊断标准的不统一,各国报道相差悬殊。国内妊娠期糖尿病发生率占孕妇的1%~5%。1997年世界卫生组织(WHO)将妊娠期糖尿病列为糖尿病的一个独立类型。1999年根据WHO和美国糖尿病协会(ADA)的建议,进一步确立了该型,按糖尿病White分级标准归入A级[1]。妊娠期糖尿病对妊娠、胎儿和新生儿的负性影响与显性糖尿病是一样的。易造成羊水过多、妊娠高血压症、巨大胎儿和死胎;新生儿易发生呼吸窘迫综合征、低血糖、低血钙及红细胞增多症;妊娠期糖尿病孕妇以后发生临床糖尿病的危险性明显增加。多次妊娠是诱发2型糖尿病的原因之一,全世界妊娠期糖尿病发生率为2%~8%,美国为2%~3%。

1 资料与方法

1.1 一般资料

本院2010年1月~2012年1月住院分娩76例妊娠期糖尿病患者,其中,48例在孕中期确诊为妊娠期糖尿病并给予治疗,28例未行孕期保健或孕中期血糖筛查,于孕34周后住院确诊妊娠期糖尿病。分别将两组分成A组和B组。1.2 方法

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